Macrodactyly and Poliosis in Tuberous Sclerosis Complex
نویسندگان
چکیده
منابع مشابه
The tuberous sclerosis complex.
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that results from mutations in the TSC1 or TSC2 genes and is associated with hamartoma formation in multiple organ systems. The neurological manifestations of TSC are particularly challenging and include infantile spasms, intractable epilepsy, cognitive disabilities, and autism. Progress over the past 15 years has demonstrated t...
متن کاملTuberous sclerosis complex.
Contrast enhanced computed tomography revealed a large well-circumscribed heterogenous retroperitoneal mass measuring 25 × 20 cm arising from the left kidney with predominant fat attenuation. Multiple smaller lesions were seen in the opposite kidney. Features were suggestive of diffuse angiomyolipomatosis of the kidneys. Hypodense lesions were also seen involving the lungslymphangioleiomyomatos...
متن کاملTuberous Sclerosis Complex in Autism
OBJECTIVE To study the prevalence rate of tuberous sclerosis complex in autistic disorder. METHODS We studied one cohort of children followed up since 2005 until 2009, with autistic disorder, to determine the incidence of tuberous sclerosis complex. We established an autistic disorder registry in 2005 at China Rehabilitation Research Center. During the 4-year period (2005-2009), we collected ...
متن کامل[Poliosis and status epilepticus as the presentation of tuberous sclerosis in an infant].
Tuberous sclerosis (TS) is a neurocutaneous syndrome with an autosomal dominant pattern of inheritance and a high penetrance. It is characterized by the appearance of hamartomatous lesions in several organs,1 and the most usual clinical signs of this disease are skin lesions, epilepsy, learning difficulties,2 and behavioral disorders. We report the case of a 51-day-old infant, born at term of n...
متن کاملTuberous sclerosis complex renal disease.
Although not as common as other genetic renal diseases such as autosomal dominant polycystic kidney disease, patients with tuberous sclerosis complex frequently have significant renal involvement. Recent revelations in the cell biology of these renal disease manifestations as well as effective therapies for tuberous sclerosis complex-related renal issues have heralded hope of improved renal sur...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Oncology
سال: 2014
ISSN: 0368-2811,1465-3621
DOI: 10.1093/jjco/hyu157